All iconic weapons
Choice-lockedBase GameWatsonAct 2

Doom Doom

Ranged · Revolver · Power · DR-5 Nova

This one sits behind a choice

The Pickup: Maelstrom. Decide before the quest closes, because the other side of that choice locks this weapon away on this save.

What it does

Fires three explosive rounds per shot with higher dismemberment chance, but more spread and recoil.

Where it sits

Loot a Maelstrom lieutenant later, if he survived the early storySide Job: Second Conflict

Pick it up before

Depends on a choice in Second Conflict; see Save Choices on Profiles

If you miss it

No known way back

Who it suits

Cool handgun build, Focus, Deadeye and Run 'N' Gun; Power/ricochet cyberware is optional · Explosives • Dismemberment

The route

Show the step by step (spoilers)

Dum Dum has to survive The Pickup, which usually means siding with Maelstrom. Later, during Second Conflict at Totentanz, things can turn into a fight. Put him down and the pistol is on him.

Confirmed by published guides, not yet by Vaexil. Nobody here has walked this one in game, so take it as a strong lead rather than a promise. Cross-checked against CD PROJEKT RED patch notes, VULKK, and the Cyberpunk Wiki, for patch 2.31 with Phantom Liberty.